The HP1α–CAF1–SetDB1-containing complex provides H3K9me1 for Suv39-mediated K9me3 in pericentric heterochromatin

Trimethylation of lysine 9 in histone H3 (H3K9me3) enrichment is a characteristic of pericentric heterochromatin. The hypothesis of a stepwise mechanism to establish and maintain this mark during DNA replication suggests that newly synthesized histone H3 goes through an intermediate methylation stat...

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Main Authors: Loyola, Alejandra, Tagami, Hideaki, Bonaldi, Tiziana, Roche, Danièle, Quivy, Jean Pierre, Imhof, Axel, Nakatani, Yoshihiro, Dent, Sharon Y R, Almouzni, Geneviève
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2009
主題:
Scientific Report
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727428/
https://ncbi.nlm.nih.gov/pubmed/19498464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.90
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