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Antifibrotic effects of pioglitazone on the kidney in a rat model of type 2 diabetes mellitus

Background. Recent evidence suggests that treatment of type 2 diabetes with thiazolidinediones [peroxisome proliferator-activated receptor-γ (PPAR-γ) agonists], ameliorates glomerulosclerosis and tubulointerstitial fibrosis in the rat kidney. In the current work, we have investigated whether these d...

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Autores principales: Toblli, Jorge E., Ferrini, Monica G., Cao, Gabriel, Vernet, Dolores, Angerosa, Margarita, Gonzalez-Cadavid, Nestor F.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727296/
https://ncbi.nlm.nih.gov/pubmed/19297362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfp103
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