Antifibrotic Effects of Pioglitazone at Low Doses on the Diabetic Rat Kidney Are Associated with the Improvement of Markers of Cell Turnover, Tubular and Endothelial Integrity, and Angiogenesis

BACKGROUND/AIMS: Pioglitazone and other thiazolidinediones are renoprotective in diabetic nephropathy at doses that normalize glycemia, presumably as a consequence of glycemic control. However, low doses of pioglitazone that did not normalize glycemia in rat models of type 2 diabetes prevented tubul...

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Detalhes bibliográficos
Principais autores: Toblli, Jorge E., Cao, Gabriel, Giani, Jorge F., Angerosa, Margarita, Dominici, Fernando P., Gonzalez-Cadavid, Nestor F.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2011
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3068565/
https://ncbi.nlm.nih.gov/pubmed/21071958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000320380
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