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G-quadruplex nucleic acids as therapeutic targets

Nucleic acid sequences containing several short runs of guanine nucleotides can form complex higher order structures, termed quadruplexes. Their occurrence has been most extensively characterised at the telomeric ends of eukaryotic chromosomes, whose DNA comprises such sequences, and where the extre...

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Main Authors: Balasubramanian, Shankar, Neidle, Stephen
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726962/
https://ncbi.nlm.nih.gov/pubmed/19515602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2009.04.637
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