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NADPH Oxidase Drives Cytokine and Neurotoxin Release from Microglia and Macrophages in Response to HIV-Tat

Previous reports have shown that the human immunodeficiency virus (HIV) regulatory protein Tat has both pro-oxidant and pro-inflammatory properties, suggesting that Tat might contribute to the neurological complications of HIV. However, the intracellular mechanisms whereby Tat triggers free radical...

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Detalles Bibliográficos
Main Authors: Turchan–Cholewo, Jadwiga, Dimayuga, Vanessa M., Gupta, Sunita, Gorospe, R.M. Charlotte, Keller, Jeffrey N., Bruce–Keller, Annadora J.
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc. 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726794/
https://ncbi.nlm.nih.gov/pubmed/18715150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2008.2097
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