Tumour-experienced T cells promote NK cell activity through trogocytosis of NKG2D and NKp46 ligands

Natural killer (NK) cells trigger cytotoxicity and interferon (IFN)-γ secretion on engagement of the natural-killer group (NKG)2D receptor or members of the natural cytotoxicity receptor (NCR) family, such as NKp46, by ligands expressed on tumour cells. However, it remains unknown whether T cells ca...

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Detalhes bibliográficos
Main Authors: Domaica, Carolina I, Fuertes, Mercedes B, Rossi, Lucas E, Girart, María V, Ávila, Damián E, Rabinovich, Gabriel A, Zwirner, Norberto W
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Scientific Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726665/
https://ncbi.nlm.nih.gov/pubmed/19498463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.92
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