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Human immunoglobulin allotypes: Possible implications for immunogenicity

More than twenty recombinant monoclonal antibodies are approved as therapeutics. Almost all of these are based on the whole IgG isotype format, but vary in the origin of the variable regions between mouse (chimeric), humanized mouse and fully human sequences; all of those with whole IgG format emplo...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Jefferis, Roy, Lefranc, Marie-Paule
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Landes Bioscience 2009
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726606/
https://ncbi.nlm.nih.gov/pubmed/20073133
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