Aryl hydrocarbon receptor suppresses intestinal carcinogenesis in Apc(Min/+) mice with natural ligands

Intestinal cancer is one of the most common human cancers. Aberrant activation of the canonical Wnt signaling cascade, for example, caused by adenomatous polyposis coli (APC) gene mutations, leads to increased stabilization and accumulation of β-catenin, resulting in initiation of intestinal carcino...

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Detalhes bibliográficos
Main Authors: Kawajiri, Kaname, Kobayashi, Yasuhito, Ohtake, Fumiaki, Ikuta, Togo, Matsushima, Yoshibumi, Mimura, Junsei, Pettersson, Sven, Pollenz, Richard S., Sakaki, Toshiyuki, Hirokawa, Takatsugu, Akiyama, Tetsu, Kurosumi, Masafumi, Poellinger, Lorenz, Kato, Shigeaki, Fujii-Kuriyama, Yoshiaki
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726415/
https://ncbi.nlm.nih.gov/pubmed/19651607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902132106
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