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Structure of human Rad51 protein filament from molecular modeling and site-specific linear dichroism spectroscopy

To get mechanistic insight into the DNA strand-exchange reaction of homologous recombination, we solved a filament structure of a human Rad51 protein, combining molecular modeling with experimental data. We build our structure on reported structures for central and N-terminal parts of pure (uncomple...

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Bibliografske podrobnosti
Main Authors: Reymer, Anna, Frykholm, Karolin, Morimatsu, Katsumi, Takahashi, Masayuki, Nordén, Bengt
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726390/
https://ncbi.nlm.nih.gov/pubmed/19587234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902723106
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