DEFECTIVE ENGRAFTMENT OF C3aR(-/-) HEMATOPOIETIC STEM PROGENITOR CELLS REVEALS A NOVEL ROLE OF THE C3a-C3aR AXIS IN BONE MARROW HOMING

We reported that complement (C) becomes activated and cleaved in bone marrow (BM) during preconditioning for hematopoietic transplantation and the third C component (C3) cleavage fragments C3a and (desArg)C3a increase responsiveness of hematopoietic stem/progenitor cells (HSPCs) to stromal derived f...

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Detalhes bibliográficos
Main Authors: Wysoczynski, Marcin, Reca, Ryan, Lee, Hakmo, Wu, Wan, Ratajczak, Janina, Ratajczak, Mariusz Z.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726273/
https://ncbi.nlm.nih.gov/pubmed/19357704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2009.73
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