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Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis

The target of rapamycin complex 1 (TORC1) is an essential multiprotein complex conserved from yeast to humans. Under favorable growth conditions, and in the absence of the macrolide rapamycin, TORC1 is active, and influences virtually all aspects of cell growth. Although two direct effectors of yeas...

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Detalhes bibliográficos
Main Authors: Huber, Alexandre, Bodenmiller, Bernd, Uotila, Aino, Stahl, Michael, Wanka, Stefanie, Gerrits, Bertran, Aebersold, Ruedi, Loewith, Robbie
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2725941/
https://ncbi.nlm.nih.gov/pubmed/19684113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.532109
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