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Alpha Interferon Induces Long-Lasting Refractoriness of JAK-STAT Signaling in the Mouse Liver through Induction of USP18/UBP43

Recombinant alpha interferon (IFN-α) is used for the treatment of viral hepatitis and some forms of cancer. During these therapies IFN-α is injected once daily or every second day for several months. Recently, the long-acting pegylated IFN-α (pegIFN-α) has replaced standard IFN-α in therapies of chr...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Sarasin-Filipowicz, Magdalena, Wang, Xueya, Yan, Ming, Duong, Francois H. T., Poli, Valeria, Hilton, Douglas J., Zhang, Dong-Er, Heim, Markus H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2725724/
https://ncbi.nlm.nih.gov/pubmed/19564419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00224-09
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