Synthesis, Anti-Hepatitis B Virus and Anti-Hepatitis C Virus Activities of 7-Deazaneplanocin A Analogues In Vitro

A series of 7-deazaneplanocin A (7-DNPA, 2) analogues were synthesized and evaluated for in vitro antiviral activity against HBV and HCV. The synthesis of target carbocyclic nucleosides were accomplished via a convergent procedure. 7-Substitutions were introduced by using 7-substituted-7-deaza heter...

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Bibliographic Details
Main Authors: Kim, Hyo-Joong, Sharon, Ashoke, Bal, Chandralata, Wang, Jianing, Allu, Madhan, Huang, Zhuhui, Murray, Michael G., Bassit, Leda, Schinazi, Raymond F., Korba, Brent, Chu, Chung K.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2725430/
https://ncbi.nlm.nih.gov/pubmed/19072694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm801418v
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