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Inflammatory cytokines stimulate the chemokines CCL2/MCP-1 and CCL7/MCP-7 through NFκB and MAPK dependent pathways in rat astrocytes

The chemokines CCL2 and CCL7 are upregulated in the brain during several neurodegenerative and acute diseases associated with infiltration of peripheral leukocytes. Astrocytes can respond to inflammatory cytokines like IL-1β and TNF-α by producing chemokines. This study aims to test the ability of I...

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Detalhes bibliográficos
Main Authors: Thompson, Wendy L., Eldik, Linda J. Van
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2725204/
https://ncbi.nlm.nih.gov/pubmed/19577550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2009.06.081
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