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Inflammatory cytokines stimulate the chemokines CCL2/MCP-1 and CCL7/MCP-7 through NFκB and MAPK dependent pathways in rat astrocytes

The chemokines CCL2 and CCL7 are upregulated in the brain during several neurodegenerative and acute diseases associated with infiltration of peripheral leukocytes. Astrocytes can respond to inflammatory cytokines like IL-1β and TNF-α by producing chemokines. This study aims to test the ability of I...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Thompson, Wendy L., Eldik, Linda J. Van
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2725204/
https://ncbi.nlm.nih.gov/pubmed/19577550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2009.06.081
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