Recurrent seizures and brain pathology after inhibition of glutamine synthetase in the hippocampus in rats

An excess of extracellular glutamate in the hippocampus has been linked to the generation of recurrent seizures and brain pathology in patients with medically intractable mesial temporal lobe epilepsy (MTLE). However, the mechanism which results in glutamate excess in MTLE remains unknown. We recent...

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Autores principales: Eid, Tore, Ghosh, Arko, Wang, Yue, Beckström, Henning, Zaveri, Hitten P., Lee, Tih-Shih W., Lai, James C. K., Malthankar-Phatak, Gauri H., de Lanerolle, Nihal C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2008
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724901/
https://ncbi.nlm.nih.gov/pubmed/18669513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awn133
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