Depletion of zebrafish essential and regulatory myosin light chains reduces cardiac function through distinct mechanisms

AIMS: Mutations in the essential myosin light chain (ELC) and regulatory myosin light chain (RLC) genes have been linked to sarcomeric hypertrophic cardiomyopathies in humans; however, the specific functions of the different myosin light chains during cardiogenesis in a vertebrate animal are not wel...

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Bibliographic Details
Main Authors: Chen, Zhenyue, Huang, Wei, Dahme, Tillman, Rottbauer, Wolfgang, Ackerman, Michael J., Xu, Xiaolei
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724891/
https://ncbi.nlm.nih.gov/pubmed/18343897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvn073
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