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EHD3 regulates early-endosome-to-Golgi transport and preserves Golgi morphology

Depletion of EHD3 affects sorting in endosomes by altering the kinetics and route of receptor recycling to the plasma membrane. Here we demonstrate that siRNA knockdown of EHD3, or its interaction partner rabenosyn-5, causes redistribution of sorting nexin 1 (SNX1) to enlarged early endosomes and di...

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Bibliografiske detaljer
Main Authors: Naslavsky, Naava, McKenzie, Jenna, Altan-Bonnet, Nihal, Sheff, David, Caplan, Steve
Format: Artigo
Sprog:Inglês
Udgivet: Company of Biologists 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724733/
https://ncbi.nlm.nih.gov/pubmed/19139087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.037051
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