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EHD3 regulates early-endosome-to-Golgi transport and preserves Golgi morphology

Depletion of EHD3 affects sorting in endosomes by altering the kinetics and route of receptor recycling to the plasma membrane. Here we demonstrate that siRNA knockdown of EHD3, or its interaction partner rabenosyn-5, causes redistribution of sorting nexin 1 (SNX1) to enlarged early endosomes and di...

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Detalhes bibliográficos
Main Authors: Naslavsky, Naava, McKenzie, Jenna, Altan-Bonnet, Nihal, Sheff, David, Caplan, Steve
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724733/
https://ncbi.nlm.nih.gov/pubmed/19139087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.037051
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