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EHD3 regulates early-endosome-to-Golgi transport and preserves Golgi morphology

Depletion of EHD3 affects sorting in endosomes by altering the kinetics and route of receptor recycling to the plasma membrane. Here we demonstrate that siRNA knockdown of EHD3, or its interaction partner rabenosyn-5, causes redistribution of sorting nexin 1 (SNX1) to enlarged early endosomes and di...

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Détails bibliographiques
Auteurs principaux: Naslavsky, Naava, McKenzie, Jenna, Altan-Bonnet, Nihal, Sheff, David, Caplan, Steve
Format: Artigo
Langue:Inglês
Publié: Company of Biologists 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724733/
https://ncbi.nlm.nih.gov/pubmed/19139087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.037051
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