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Spontaneous phosphoinositide 3-kinase signaling dynamics drive spreading and random migration of fibroblasts
During directed cell migration (chemotaxis), cytoskeletal dynamics are stimulated and spatially biased by phosphoinositide 3-kinase (PI3K) and other signal transduction pathways. Live-cell imaging using total internal reflection fluorescence (TIRF) microscopy revealed that, in the absence of soluble...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Company of Biologists
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2724728/ https://ncbi.nlm.nih.gov/pubmed/19126672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.037564 |
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