Spontaneous phosphoinositide 3-kinase signaling dynamics drive spreading and random migration of fibroblasts

During directed cell migration (chemotaxis), cytoskeletal dynamics are stimulated and spatially biased by phosphoinositide 3-kinase (PI3K) and other signal transduction pathways. Live-cell imaging using total internal reflection fluorescence (TIRF) microscopy revealed that, in the absence of soluble...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Weiger, Michael C., Wang, Chun-Chao, Krajcovic, Matej, Melvin, Adam T., Rhoden, John J., Haugh, Jason M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Company of Biologists 2009
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724728/
https://ncbi.nlm.nih.gov/pubmed/19126672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.037564
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