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Subchronic infusion of the product of inflammation prostaglandin J2 models sporadic Parkinson's disease in mice

BACKGROUND: Chronic neuroinflammation is implicated in Parkinson's disease (PD). Inflammation involves the activation of microglia and astrocytes that release high levels of prostaglandins. There is a profound gap in our understanding of how cyclooxygenases and their prostaglandin products redi...

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Détails bibliographiques
Auteurs principaux: Pierre, Sha-Ron, Lemmens, Marijke AM, Figueiredo-Pereira, Maria E
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724408/
https://ncbi.nlm.nih.gov/pubmed/19630993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-6-18
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