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Practical Therapeutic Drug Management in HIV-Infected Patients: Use of Population Pharmacokinetic Models Supplemented by Individualized Bayesian Dose Optimization

Individualized, model-based, target-oriented optimal concentration-controlled dosing of HIV medications can be beneficial to patients for whom there are limited dosing guidelines, such as children, adolescents, or patients with altered physiologic function. Barriers to this approach include lack of...

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Detalles Bibliográficos
Main Authors: Neely, Michael, Jelliffe, Roger
Formato: Artigo
Idioma:Inglês
Publicado: 2008
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724306/
https://ncbi.nlm.nih.gov/pubmed/18635757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0091270008321789
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