Activation of the nitric oxide-cGMP pathway reduces phasic contractions in neonatal rat bladder strips via protein kinase G

Nitric oxide (NO), a neurotransmitter in the lower urinary tract, stimulates soluble guanylyl cyclase (sGC) and in turn cGMP-dependent protein kinase G (PKG) to modulate a number of downstream targets. NO donors reduce bladder hyperactivity in some pathological models but do not affect normal bladde...

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Bibliografiset tiedot
Päätekijät: Artim, Debra E., Kullmann, F. Aura, Daugherty, Stephanie L., Wu, Hsi-Yang, de Groat, William C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Physiological Society 2009
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Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724251/
https://ncbi.nlm.nih.gov/pubmed/19493964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00207.2009
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