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Determination of S-Adenosylmethionine and S-Adenosylhomocysteine by LC–MS/MS and evaluation of their stability in mice tissues
S-Adenosylmethionine (SAM) serves as a methyl donor in biological transmethylation reactions. S-Adenosylhomocysteine (SAH) is the product as well as the inhibitor of transmethylations and the ratio SAM/SAH is regarded as the measure of methylating capacity (“methylation index”). We present a rapid a...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Elsevier
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2724122/ https://ncbi.nlm.nih.gov/pubmed/19502114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2009.05.039 |
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