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Titanium particles stimulate COX-2 expression in synovial fibroblasts through an oxidative stress-induced, calpain-dependent, NF-κB pathway
In prosthetic loosening, bone resorption is induced by wear debris particles generated from the artificial joint articulation. Our prior work showed that synovial-like fibroblasts respond to titanium particles by producing receptor activator of NF-κB ligand (RANKL), a critical activator of osteoclas...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2724098/ https://ncbi.nlm.nih.gov/pubmed/19494233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00597.2008 |
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