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Uric acid attenuates trophoblast invasion and integration into endothelial cell monolayers

Hyperuricemia develops as early as 10 wk of gestation in women who later develop preeclampsia. At this time the invasive trophoblast cells are actively remodeling the uterine spiral arterioles, integrating into and finally replacing the vascular endothelial lining. In the nonpregnant population uric...

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Main Authors: Bainbridge, Shannon A., Roberts, James M., von Versen-Höynck, Frauke, Koch, Jessa, Edmunds, Lia, Hubel, Carl A.
格式: Artigo
語言:Inglês
出版: American Physiological Society 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724097/
https://ncbi.nlm.nih.gov/pubmed/19535510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00593.2008
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