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eNOS mediates TO90317 treatment induced angiogenesis and functional outcome after stroke in mice

BACKGROUND AND PURPOSE: TO901317, a synthetic liver X receptor (LXR) agonist, elevates high-density lipoprotein cholesterol (HDL-C) in mice. We tested the hypothesis that TO901317 treatment of stroke promotes angiogenesis and vascular maturation and improves functional outcome after stroke by increa...

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Bibliographic Details
Main Authors: Chen, Jieli, Cui, Xu, Zacharek, Alex, Roberts, Cynthia, Chopp, Michael
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724074/
https://ncbi.nlm.nih.gov/pubmed/19443804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.108.545095
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