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Angiopoietin-Tie2 pathway mediates type 2 diabetes induced vascular damage after cerebral stroke

We investigated the changes and the molecular mechanisms of cerebral vascular damage after stroke in type-2 diabetic (T2DM) mice. Adult male db/db T2DM and wild-type (WT) mice were subjected to transient middle cerebral artery occlusion (MCAo) and sacrificed 24 hours after MCAo. T2DM-mice exhibited...

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Bibliografiske detaljer
Main Authors: Cui, Xu, Chopp, Michael, Zacharek, Alex, Ye, Xinchun, Roberts, Cynthia, Chen, Jieli
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096677/
https://ncbi.nlm.nih.gov/pubmed/21515377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.04.005
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