Regulatory T Cells Suppress Innate Immunity in Kidney Ischemia-Reperfusion Injury

Both innate and adaptive mechanisms participate in the pathogenesis of kidney ischemia-reperfusion injury (IRI), but the role of regulatory immune mechanisms is unknown. We hypothesized that the anti-inflammatory effects of CD4(+)CD25(+)FoxP3(+) regulatory T cells (Tregs) protect against renal IRI....

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Autores principales: Kinsey, Gilbert R., Sharma, Rahul, Huang, Liping, Li, Li, Vergis, Amy L., Ye, Hong, Ju, Shyr-Te, Okusa, Mark D.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Nephrology 2009
Materias:
Basic Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723989/
https://ncbi.nlm.nih.gov/pubmed/19497969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008111160
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