Chronic hypoxia inhibits MMP-2 activation and cellular invasion in human cardiac myofibroblasts

Cardiac myofibroblasts are pivotal to adaptive remodelling after myocardial infarction (MI). These normally quiescent cells invade and proliferate as a wound healing response, facilitated by activation of matrix metalloproteinases, particularly MMP-2. Following MI these reparative events occur under...

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Detalhes bibliográficos
Main Authors: Riches, Kirsten, Morley, Michael E., Turner, Neil A., O'Regan, David J., Ball, Stephen G., Peers, Chris, Porter, Karen E.
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2009
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723933/
https://ncbi.nlm.nih.gov/pubmed/19523958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2009.06.002
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