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Adhesive Dynamics Simulations of the Mechanical Shedding of L-Selectin from the Neutrophil Surface

Here we accurately recreate the mechanical shedding of L-selectin and its effect on the rolling behavior of neutrophils in vitro using the Adhesive Dynamics simulation by incorporating the shear-dependent shedding of L-selectin. We have previously shown that constitutively expressed L-selectin is cl...

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Main Authors: Lee, Dooyoung, Caputo, Kelly E., Hammer, Daniel A., King, Michael R.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723182/
https://ncbi.nlm.nih.gov/pubmed/19486904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2009.05.014
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