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Vector-mediated gene transfer engenders long-lived neutralizing activity and protection against SIV infection in monkeys

The holy grail for HIV vaccine development is an immunogen that elicits persisting antibodies with broad neutralizing activity against field strains of the virus. Unfortunately, very little progress has been made in finding or designing such immunogens. Using the SIV model, we have taken a markedly...

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Detalhes bibliográficos
Main Authors: Johnson, Philip R, Schnepp, Bruce C, Zhang, Jianchao, Connell, Mary J, Greene, Sean M, Yuste, Eloisa, Desrosiers, Ronald C, Clark, K Reed
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723177/
https://ncbi.nlm.nih.gov/pubmed/19448633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.1967
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