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The interactome of the amyloid β precursor protein family members is shaped by phosphorylation of their intracellular domains

BACKGROUND: Brain tissue from patients with Alzheimer's disease has shown an increase of phosphorylation of Tyr-682, located on the conserved Y682ENPTY motif, and Thr-668 residues, both in the intracellular domain (AID) of amyloid β precursor protein (APP), although the role of these two residu...

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Bibliographic Details
Main Authors: Tamayev, Robert, Zhou, Dawang, D'Adamio, Luciano
Format: Artigo
Language:Inglês
Published: BioMed Central 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723102/
https://ncbi.nlm.nih.gov/pubmed/19602287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-4-28
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