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Stage-dependent modes of Pax6-Sox2 epistasis regulate lens development and eye morphogenesis

The transcription factors Pax6 and Sox2 have been implicated in early events in lens induction and have been proposed to cooperate functionally. Here, we investigated the activity of Sox2 in lens induction and its genetic relationship to Pax6 in the mouse. Conditional deletion of Sox2 in the lens pl...

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Detalles Bibliográficos
Main Authors: Smith, April N., Miller, Leigh-Anne, Radice, Glenn, Ashery-Padan, Ruth, Lang, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado: The Company of Biologists Limited 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723069/
https://ncbi.nlm.nih.gov/pubmed/19666824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.037341
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