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Stage-dependent modes of Pax6-Sox2 epistasis regulate lens development and eye morphogenesis

The transcription factors Pax6 and Sox2 have been implicated in early events in lens induction and have been proposed to cooperate functionally. Here, we investigated the activity of Sox2 in lens induction and its genetic relationship to Pax6 in the mouse. Conditional deletion of Sox2 in the lens pl...

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Bibliografiske detaljer
Main Authors: Smith, April N., Miller, Leigh-Anne, Radice, Glenn, Ashery-Padan, Ruth, Lang, Richard A.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Limited 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723069/
https://ncbi.nlm.nih.gov/pubmed/19666824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.037341
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