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Islet-to-LMO stoichiometries control the function of transcription complexes that specify motor neuron and V2a interneuron identity

LIM transcription factors bind to nuclear LIM interactor (Ldb/NLI/Clim) in specific ratios to form higher-order complexes that regulate gene expression. Here we examined how the dosage of LIM homeodomain proteins Isl1 and Isl2 and LIM-only protein Lmo4 influences the assembly and function of complex...

詳細記述

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書誌詳細
主要な著者: Song, Mi-Ryoung, Sun, Yunfu, Bryson, Ami, Gill, Gordon N., Evans, Sylvia M., Pfaff, Samuel L.
フォーマット: Artigo
言語:Inglês
出版事項: Company of Biologists 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723064/
https://ncbi.nlm.nih.gov/pubmed/19666821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.037986
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