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Islet-to-LMO stoichiometries control the function of transcription complexes that specify motor neuron and V2a interneuron identity
LIM transcription factors bind to nuclear LIM interactor (Ldb/NLI/Clim) in specific ratios to form higher-order complexes that regulate gene expression. Here we examined how the dosage of LIM homeodomain proteins Isl1 and Isl2 and LIM-only protein Lmo4 influences the assembly and function of complex...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Company of Biologists
2009
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2723064/ https://ncbi.nlm.nih.gov/pubmed/19666821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.037986 |
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