Islet-to-LMO stoichiometries control the function of transcription complexes that specify motor neuron and V2a interneuron identity

LIM transcription factors bind to nuclear LIM interactor (Ldb/NLI/Clim) in specific ratios to form higher-order complexes that regulate gene expression. Here we examined how the dosage of LIM homeodomain proteins Isl1 and Isl2 and LIM-only protein Lmo4 influences the assembly and function of complex...

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Hlavní autoři: Song, Mi-Ryoung, Sun, Yunfu, Bryson, Ami, Gill, Gordon N., Evans, Sylvia M., Pfaff, Samuel L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Company of Biologists 2009
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723064/
https://ncbi.nlm.nih.gov/pubmed/19666821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.037986
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