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Cell-nonautonomous function of Id1 in the hematopoietic progenitor cell niche

Development of hematopoietic stem cells (HSCs) and their immediate progeny is maintained by the interaction with cells in the microenvironment. We found that hematopoiesis was dysregulated in Id1(−/−) mice. Although the frequency of HSCs in Id1(−/−) bone marrow was increased, their total numbers rem...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Suh, Hyung Chan, Ji, Ming, Gooya, John, Lee, Michael, Klarmann, Kimberly D., Keller, Jonathan R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723014/
https://ncbi.nlm.nih.gov/pubmed/19478045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-09-179788
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