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DNMT3B interacts with constitutive centromere protein CENP-C to modulate DNA methylation and the histone code at centromeric regions

DNA methylation is an epigenetically imposed mark of transcriptional repression that is essential for maintenance of chromatin structure and genomic stability. Genome-wide methylation patterns are mediated by the combined action of three DNA methyltransferases: DNMT1, DNMT3A and DNMT3B. Compelling l...

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Main Authors: Gopalakrishnan, Suhasni, Sullivan, Beth A., Trazzi, Stefania, Della Valle, Giuliano, Robertson, Keith D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722982/
https://ncbi.nlm.nih.gov/pubmed/19482874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp256
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