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DNMT3B interacts with constitutive centromere protein CENP-C to modulate DNA methylation and the histone code at centromeric regions

DNA methylation is an epigenetically imposed mark of transcriptional repression that is essential for maintenance of chromatin structure and genomic stability. Genome-wide methylation patterns are mediated by the combined action of three DNA methyltransferases: DNMT1, DNMT3A and DNMT3B. Compelling l...

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Hlavní autoři: Gopalakrishnan, Suhasni, Sullivan, Beth A., Trazzi, Stefania, Della Valle, Giuliano, Robertson, Keith D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722982/
https://ncbi.nlm.nih.gov/pubmed/19482874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp256
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