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Partial loss of GATA factor Pannier impairs adult heart function in Drosophila
The GATA transcription factor encoded by pannier (pnr) is a critical regulator of heart progenitor formation in Drosophila. Mutations in GATA4, the mammalian homolog of pnr, have also been implicated in causing human cardiac disease in a haploinsufficient manner. Mouse models of Gata4 loss-of-functi...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2722980/ https://ncbi.nlm.nih.gov/pubmed/19494035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp254 |
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