A Phase 1 study of the blood-stage malaria vaccine candidate AMA1-C1/Alhydrogel® with CPG 7909, using two different formulations and dosing intervals

A Phase 1 study was conducted in 24 malaria naïve adults to assess the safety and immunogenicity of the recombinant protein vaccine Apical Membrane Antigen 1-Combination 1 (AMA1-C1)/Alhydrogel with CPG 7909 in two different formulations (phosphate buffer and saline), and given at two different dosin...

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Bibliographische Detailangaben
Hauptverfasser: Ellis, Ruth D., Mullen, Gregory E., Pierce, Mark, Martin, Laura B., Miura, Kazutoyo, Fay, Michael P., Long, Carole A., Shaffer, Donna, Saul, Allan, Miller, Louis H., Durbin, Anna P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722923/
https://ncbi.nlm.nih.gov/pubmed/19410624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.04.077
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