Embryonic motor axon development in the severe SMA mouse

Spinal muscular atrophy (SMA) is caused by reduced levels of survival motor neuron (SMN) protein. Previously, cultured SMA motor neurons showed reduced growth cone size and axonal length. Furthermore, reduction of SMN in zebrafish resulted in truncation followed by branching of motor neuron axons. I...

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Hlavní autoři: McGovern, Vicki L., Gavrilina, Tatiana O., Beattie, Christine E., Burghes, Arthur H.M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722893/
https://ncbi.nlm.nih.gov/pubmed/18603534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn189
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