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Prohibitin and the SWI/SNF ATPase subunit BRG1 are required for effective androgen antagonist-mediated transcriptional repression of androgen receptor-regulated genes

Androgen antagonists or androgen deprivation are the primary therapeutic modalities for the treatment of prostate cancer. Invariably, however, the disease becomes progressive and unresponsive to androgen ablation therapy (hormone refractory). The molecular mechanisms by which androgen antagonists in...

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Hlavní autoři: Dai, Yan, Ngo, Duyen, Jacob, Johanna, Forman, Lora W., Faller, Douglas V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722849/
https://ncbi.nlm.nih.gov/pubmed/18487222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgn117
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