A Vasculature-Targeting Regimen of Pre-Operative Docetaxel with or without Bevacizumab for Locally Advanced Breast Cancer: Impact on Angiogenic Biomarkers

PURPOSE: Taxanes have effects on angiogenesis causing difficulties in separating biologic effects of chemotherapy from those due to angiogenesis inhibitors. This randomized phase II trial was designed to evaluate the additional biomarker effect on angiogenesis when bevacizumab is added to docetaxel....

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Bibliographische Detailangaben
Hauptverfasser: Baar, Joseph, Silverman, Paula, Lyons, Janice, Fu, Pingfu, Abdul-Karim, Fadi, Ziats, Nicholas, Wasman, Jay, Hartman, Paul, Jesberger, John, Dumadag, Leda, Hohler, Erin, Leeming, Rosemary, Shenk, Robert, Chen, Helen, McCrae, Keith, Dowlati, Afshin, Remick, Scot C., Overmoyer, Beth
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722840/
https://ncbi.nlm.nih.gov/pubmed/19417018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-2917
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