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Compression regulates mitotic spindle length by a mechanochemical switch at the poles

BACKGROUND: Although the molecules involved in mitosis are becoming better characterized, we still lack an understanding of the emergent mechanical properties of the mitotic spindle. For example, we cannot explain how spindle length is determined. To gain insight into how forces are generated and re...

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Detalhes bibliográficos
Main Authors: Dumont, Sophie, Mitchison, Timothy J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722833/
https://ncbi.nlm.nih.gov/pubmed/19540117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2009.05.056
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