Genetic and antibody-mediated reprogramming of natural killer cell missing-self recognition in vivo

Natural killer (NK) cells are lymphocytes of the innate immune system able to recognize and kill tumors lacking self-MHC class I molecules. This “missing-self” recognition is mediated by the lack of engagement of MHC class I-specific inhibitory NK cell receptors that include the killer cell Ig-like...

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Detalhes bibliográficos
Main Authors: Sola, Caroline, André, Pascale, Lemmers, Céline, Fuseri, Nicolas, Bonnafous, Cécile, Bléry, Mathieu, Wagtmann, Nicolai R., Romagné, François, Vivier, Eric, Ugolini, Sophie
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722344/
https://ncbi.nlm.nih.gov/pubmed/19561305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901653106
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