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Anti-KIR antibody enhancement of anti-lymphoma activity of natural killer cells as monotherapy and in combination with anti-CD20 antibodies

Natural killer (NK) cells mediate antilymphoma activity by spontaneous cytotoxicity and antibody-dependent cell-mediated cytotoxicity (ADCC) when triggered by rituximab, an anti-CD20 monoclonal antibody (mAb) used to treat patients with B-cell lymphomas. The balance of inhibitory and activating sign...

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Detalhes bibliográficos
Main Authors: Kohrt, Holbrook E., Thielens, Ariane, Marabelle, Aurelien, Sagiv-Barfi, Idit, Sola, Caroline, Chanuc, Fabien, Fuseri, Nicolas, Bonnafous, Cécile, Czerwinski, Debra, Rajapaksa, Amanda, Waller, Erin, Ugolini, Sophie, Vivier, Eric, Romagné, François, Levy, Ronald, Bléry, Mathieu, André, Pascale
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907754/
https://ncbi.nlm.nih.gov/pubmed/24326534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-08-519199
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