Impaired defense mechanism against inflammation, hyperalgesia, and airway hyperreactivity in somatostatin 4 receptor gene-deleted mice

We have shown that somatostatin released from activated capsaicin-sensitive nociceptive nerve endings during inflammatory processes elicits systemic anti-inflammatory and analgesic effects. With the help of somatostatin receptor subtype 4 gene–deleted mice (sst(4)(−/−)), we provide here several line...

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Autori principali: Helyes, Zsuzsanna, Pintér, Erika, Sándor, Katalin, Elekes, Krisztián, Bánvölgyi, Ágnes, Keszthelyi, Dániel, Szőke, Éva, Tóth, Dániel M., Sándor, Zoltán, Kereskai, László, Pozsgai, Gábor, Allen, Jeremy P., Emson, Piers C., Markovics, Adrienn, Szolcsányi, János
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2009
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722291/
https://ncbi.nlm.nih.gov/pubmed/19622729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900681106
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