Effects of the somatostatin receptor subtype 4 selective agonist J-2156 on sensory neuropeptide release and inflammatory reactions in rodents

BACKGROUND AND PURPOSE: Substance P (SP) and calcitonin gene-related peptide (CGRP) released from capsaicin-sensitive sensory nerves induce local neurogenic inflammation; somatostatin exerts systemic anti-inflammatory actions presumably via sst(4)/sst(1) receptors. This study investigates the effect...

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Detalhes bibliográficos
Main Authors: Helyes, Z, Pintér, E, Németh, J, Sándor, K, Elekes, K, Szabó, Á, Pozsgai, G, Keszthelyi, D, Kereskai, L, Engström, M, Wurster, S, Szolcsányi, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2006
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978437/
https://ncbi.nlm.nih.gov/pubmed/16953190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706876
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