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Murine Polyomavirus encodes a microRNA that cleaves early RNA transcripts but is not essential for experimental infection

MicroRNAs are small regulatory RNAs that post-transcriptionally regulate gene expression and can be encoded by viral as well as cellular genomes. The functions of most viral miRNAs are unknown and few have been studied in an in vivo context. Here we show that the murine polyomavirus (PyV) encodes a...

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Bibliografiske detaljer
Main Authors: Sullivan, Christopher S., Sung, Chang K., Pack, Christopher D., Grundhoff, Adam, Lukacher, Aron E., Benjamin, Thomas L., Ganem, Don
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722155/
https://ncbi.nlm.nih.gov/pubmed/19272626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.02.017
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